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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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3-Bromopyruvic acid is an analogue of pyruvate and a potent hexokinase (HK)-II inhibitor with high tumor selectivity. It inhibits cell growth and induces apoptosis by interfering with glycolysis. It also induces autophagy by stimulating ROS formation in breast cancer cells, and exhibits antimicrobial activities.
Inhibits cell growth and induces apoptosis by interfering with glycolysis
Induces autophagy by stimulating ROS formation in breast cancer cells
Exhibits antimicrobial activities
Potent hexokinase (HK)-II inhibitor
Shows high tumor selectivity
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3-Bromopyruvic acid, also known as bromopyruvic acid or 3-BrPA, is a pyruvate analogue that acts as a potent hexokinase (HK)-II inhibitor. It demonstrates high tumor selectivity, inhibiting cell growth and inducing apoptosis by disrupting glycolysis. This compound also promotes autophagy through stimulating ROS formation in breast cancer cells and exhibits antimicrobial properties.
Potent hexokinase (HK)-II inhibitor
High tumor selectivity
Inhibits cell growth
Induces apoptosis by interfering with glycolysis
Induces autophagy by stimulating ROS formation in breast cancer cells
Exhibits antimicrobial activities
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
3-Bromopyruvic acid (5 g), Adipogen Life Sciences. Chemical. CAS: 1113-59-3. Formula: C3H3BrO3. MW: 167. Synthetic. Cell-permeable pyruvic acid derivative. Hexokinase II (HK2) inhibitor. Useful agent for immunometabolism research. Antitumor agent. Inhibits the rate limiting step of glycolysis and effectively suppress tumor survival in vitro and in vivo. Displays potent cytotoxic activity against cancer cells with mitochondrial respiratory defects and cells in hypoxic environment. Antifungal agent (anticryptococcal). Also used as affinity label for cysteine residues and cross-linker between nucleic acids and proteins.
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Indole-3-pyruvic acid is an endogenous tryptophan metabolite and aryl hydrocarbon receptor (AHR) agonist supplied as a solid or a ready-to-use 10 mM solution in DMSO for biochemical and in vitro research. The material is provided with validated purity, molecular weight, and solubility data to support experimental reproducibility.
High purity suitable for research applications.
Ready-to-use 10 mM solution in DMSO for rapid assay setup.
Available as solid for custom dissolution and storage.
Documented solubility in DMSO and water with handling recommendations.
Molecular weight and formula supplied for dosing and calculations.
Appropriate for biochemical and pharmacological assays.
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Trans-Clopenthixol is an antibiotic (E)-isomer that does not exhibit a neuroleptic effect. It has been shown to inhibit the growth of *Pseudomonas aeruginosa* and *Plasmodium falciparum* in vitro.
Antibiotic without neuroleptic effect
Inhibits *Pseudomonas aeruginosa* in vitro
Inhibits *Plasmodium falciparum* in vitro
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