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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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SPR719 (VXc-486) is an orally active gyrase B inhibitor that exhibits bactericidal activity. It shows promise for research into lung diseases caused by non-tuberculous mycobacteria (NTM).
Potently inhibits multiple agent-sensitive and drug-resistant isolates of Mycobacterium tuberculosis.
Minimum Inhibitory Concentrations (MICs) against Mycobacterium tuberculosis range from 0.03 to 0.30 μg/ml for agent-sensitive isolates and 0.08 to 5.48 μg/ml for drug-resistant isolates.
Reduces mycobacterial burden in a chronic tuberculosis infection model in mice when administered orally.
Inhibits M. tuberculosis replication in macrophages with an MIC range of 0.125-0.25 μg/mL.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Medchemexpress, HY-12390 5mg Lofepramine CAS:23047-25-8 Lofepramine (Lopramine) is a potent tricyclic antidepressant and is extensively metabolised to Desipramine. The antidepressant activity of Lofepramine stems from the facilitation of noradrenergic neurotransmission by uptake inhibition. Lofepramine may also potentiate serotoninergic neurotransmission by inhibition of the neuronal uptake of serotonin and the enzyme tryptophan pyrrolase. Lofepramine has significant anxiolytic efficacy in addition to its antidepressant properties. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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1 3-Dihydroxyacetone (DHA) the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans 1 3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227)[1][2]
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